Laryngopharyngeal reflux disease (LPRD) is known in medical circles as a "silent disease." It is difficult to detect because conventional pH measurement systems cannot function properly above the esophagus due to sensor dry-out. The Restech Dx-pH Probe™ incorporates the first and only pH sensor capable of self-condensing, thus facilitating reliable measurement and recording of aerosolized reflux in the upper airway.
Like scores of other physicians around the country, Dr. Mahdavi turned to the Restech Dx-System not only to detect a stealthy and common disease state, but also to gauge the effectiveness of empirically prescribed Proton Pump Inhibitor (PPI) therapy (Nexium®, AcipHex®, Prilosec®).
A recent meta-analysis of empiric treatment of LPR with PPI trials, published by Karkos and Wilson (Laryngoscope), concluded that "the few randomized, controlled trials have failed to demonstrate superiority of PPIs over placebo for treatment of suspected LPR." This new evidence is making some doctors think twice before prescribing PPIs without a positive pH study.
Dr. Mahdavi asserted, "After performing several studies with the Dx-System, I will begin to pre-screen patients with the Restech Dx-System as a filter for patients who may or may not need PPI therapy. We feel this system will speed up patient diagnoses and cut down on patient costs in the end."
Leo Roucher, CEO of Restech, added, "One of our end-goals is to cut down on the overall cost of treating patients with reflux. If our system can indicate whether or not PPI therapy is necessary before a patient is treated, that would be one great outcome for our product."
Dr. Mahdavi is Medical Director for the San Diego Ear, Head and Neck Medical Center in La Jolla, California. He is one of a growing number of the nation's most reputable and published physicians using the Restech Dx-System.
Restech is a leader in developing world-class medical technologies assisting physicians in the diagnosis of reflux related health problems. For more information on the Dx-pH Measurement System, please contact Debra Krahel or Bryan Buljat at (800) 352-1512 or visit restech-corp.
View drug information on Aciphex; Nexium; Prilosec.
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